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However, proteasome inhibition activates antioxidant and HSP signaling pathways, which may result in neuroprotection early after SCI and an apoptotic response at later time points (Yew et al., 2005

GPX1 KO mice developed normally, indicating that the lack of antioxidant defenses could be compensated for by other proteins, or that oxidative stress under normal conditions did not cause any harm

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Reddy BVija, Milshteyn B, Charlop-Powers A, Brady Z SF (2014) eSNaPD: a versatile, web-based bioinformatics platform for surveying and mining natural product biosynthetic diversity from metagenomes